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IDG e-Symposium

Spring 2021



Illuminating the Druggable Genome (IDG), a NIH Common Fund sponsored consortium, is organizing an e(lectronic)-Symposium series during the Spring of 2021. This series aims to offer the scientific community opportunities to learn about exciting new developments from IDG’s research resulting in new experimental resources and digital tools illuminating the understudied targets in three main druggable protein families: GPCR, kinase and ion channels... and beyond. This IDG consortium consists of a network of Data and Resource Generation Centers (DRGCs), each focusing their research on one of the three protein families, the Knowledge Management Center (KMC) organizing data and integrated informatics tools across various resources to illuminate understudied protein targets, and the Resource Dissemination and Outreach Center (RDOC) facilitating annotation and distribution of resources brought forth to shed light on to targets. In the spring of 2019, three additional groups joined IDG focusing on making Cutting Edge Informatics Tools for Illuminating the Druggable Genome (CEIT).

To foster greater knowledge and exposure, IDG will invite external speakers to share their work on the symposium session’s theme. Examples of themes are; Kinase, GPCR, Ion Channel, Informatic databases and tools, Machine Learning, Novel Technologies, Proteomics, Bio-Assays, Mouse resources, Compound screening. Each 1-hour IDG e-Symposium session will feature two speakers giving 20 minute talks and allowing for some “mingling” and Live Q&A. The meeting platform would be Zoom Webinar. Advertisement and announcements of IDG e-Symposium Series will be made via IDG social media outlets, Newsletter, and website. The symposium sessions will be recorded and posted on IDG YouTube Channel and DruggableGenome.net.

Spring 2021 - March, April, May
Day: Odd-week Tuesday (March 16, 30; April 6, 20; May 4, 18) - 6 total
Time: 9-10 AM PT /10-11 AM MT / 12-1 PM ET / 17-18 UK

Date: May 18th, 2021
Time: 9-10 AM PT / 10-11 AM MT / 12-1 PM ET / 17-18 UK
Theme: IDG-associate R03 outcomes
Speaker: Dr. Thomas Green, PhD, University of Texas Medical Branch, "GPR12 in the nucleus accumbens and addiction: electrophysiology and behavior".
Speaker: : Dr. Daniel G. Isom, PhD, University of Miami Miller School of Medicine, "University of Miami Miller School of Medicine".
Tags: #idg #drugdiscovery #gpcr #protons #addiction #electrophysiology
Registration: https://idg-e-symposium-series-may182021.eventbrite.com/

Date: May 4th, 2021
Time: 9-10 AM PT / 10-11 AM MT / 12-1 PM ET / 17-18 UK
Theme: CEIT, Informatic Tools
Invited speaker: Dr. Paul W. Sternberg, PhD, California Institute of Technology, "Curating, integrating and presenting information about model organisms at the Alliance of Genome Resources".
IDG speaker: Dr. Lincoln Stein, MD PhD, Ontario Institute for Cancer Research and co-PI of Reactome, "Guilt by Association: A Few Tricks for Finding and Characterizing Cancer-Associated Genes".
Tags: #idg #informatics #informaticstools #drugdiscovery #genome #pathway #modelorganisms #cancer #pathways
Registration: https://idg-e-symposium-series-may042021.eventbrite.com/

Date: April 20th, 2021
Time: 9-10 AM PT / 10-11 AM MT / 12-1 PM ET / 17-18 UK
Theme: Ion Channel
Invited speaker: Dr. Srinivas Niranj Chandrasekaran, PhD, Broad Institute, "Accelerating drug discovery with the power of microscopy".
IDG speaker: Dr. Stefan Feske, MD, New York University School of Medicine, "Identification of novel ion channels and transporters in immune cells".
Tags: #idg #ionchannels #transporters #drugdiscovery #immunecells #microscopy
Registration: https://idg-e-symposium-series-april202021.eventbrite.com/

Date: April 6th, 2021
Time: 9-10 AM PT / 10-11 AM MT / 12-1 PM ET / 17-18 UK
Theme: GPCR
Invited speaker: Dr. Aashish Manglik, PhD, University of California San Francisco, "Fishing with new bait: biochemical approaches to interrogate orphan GPCR function".
IDG speaker: Dr. Can Cao, PhD, DRGC-GPCR, "Structural and functional study of orphan receptor".
Tags: #idg #gpcr #drugdiscovery #orphangpcr #proteinstructure #proteinfunction #biochemical
Registration: https://idg-e-symposium-series-april062021.eventbrite.com

Date: March 30th, 2021
Time: 9-10 AM PT / 10-11 AM MT / 12-1 PM ET / 17-18 UK
Theme: Kinase
Invited speaker: Dr. Martin Golkowski, PhD, University of Washington, "Targeting Phenotypic Transitions to Overcome Cancer Metastasis and Therapy Resistance".
IDG speaker: Dr. Gary Johnson, PI for DRGC-Kinase, "Plasticity of the Human Kinome Responding to Targeted Kinase Inhibition".
Tags: #idg #kinases #drugdiscovery #CellPlasticity #Cancer #metastasis #drugresistance #therapyresistance
Registration: click this link https://idg-e-symposium-series-march302021.eventbrite.com

Date: March 16th, 2021
Time: 9-10 AM PT / 10-11 AM MT / 12-1 PM ET / 16-17 UK
Theme: Informatic Platforms and Drug Discovery
Invited speaker: Dr. Ian Dunham, Director of Open Targets at EMBL-EBI, "Identifying and prioritising drug targets with the Open Targets Platform and Open Targets Genetics"
IDG speaker: Dr. Tudor Oprea, PI for KMC and RDOC, "Illuminating the Druggable Genome: Drugs, Targets, Phenotypes and Diseases"
Tags: #idg #drugdiscovery #drugrepurposing #rarediseases #druggability #AI #machinelearning
Registration: click this link https://idg-e-symposium-series-march162021.eventbrite.com