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Illuminating The Druggable Genome Resource Dissemination And Outreach Center

Tudor Oprea, M.D., Ph.D.
Chief, Translational Informatics Division
Department of Internal Medicine at Health Science Center

Larry A. Sklar, Ph.D.
Regents Professor of Pathology and Distinguished University Professor
Director, UNM Center for Molecular Discovery
Co-Leader Program in Cancer Therapeutics, UNM Comprehensive Cancer Center
Director, Drug Rescue, Repurposing, and Repositioning Network, UNM CTSC
Associate Director and Maralyn S. Budke/Robert E. Anderson Endowed Chair in Cancer Drug Discovery
Department of Pathology (UNM)


The RDOC collaboration extends to UNM. Dr. Larry Sklar heads the Management and Administration Core (MAC), which support and coordinates across the entire IDG Consortium. Additional work will be focused on formulating policy and guidelines that will govern the collaboration and sharing of resources, data and information amongst IDG members and general scientific community. Dr. Tudor Oprea leads IDG outreach to other consortia or groups and develops training programs for PHAROS and informatics tools.

NIH grant number: 1U24TR002278-01

RDOC at UNM publications:

  1. TIN-X: target importance and novelty explorer. Cannon DC, Yang JJ, Mathias SL, Ursu O, Mani S, Waller A, Schürer SC, Jensen LJ, Sklar LA, Bologa CG, Oprea TI. Bioinformatics. 2017 Aug 15;33(16):2601-2603. doi: 10.1093/bioinformatics/btx200. PMID: 28398460.
  2. Pharos: Collating protein information to shed light on the druggable genome. Nguyen DT, Mathias S, Bologa C, Brunak S, Fernandez N, Gaulton A, Hersey A, Holmes J, Jensen LJ, Karlsson A, Liu G, Ma'ayan A, Mandava G, Mani S, Mehta S, Overington J, Patel J, Rouillard AD, Schürer S, Sheils T, Simeonov A, Sklar LA, Southall N, Ursu O, Vidovic D, Waller A, Yang J, Jadhav A, Oprea TI, Guha R. Nucleic Acids Res. 2017 Jan 4;45(D1):D995-D1002. doi: 10.1093/nar/gkw1072. Epub 2016 Nov 29. PMID: 27903890,  PMCID: PMC5210555