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e-IDG Symposium

Fall 2021



Illuminating the Druggable Genome (IDG), a NIH Common Fund sponsored consortium, is staring up the next round of their e-IDG Symposium series for the Fall of 2021. We encourage all to join the five 1-hour sessions to learn about exciting new developments from IDG’s research resulting in new experimental resources and digital tools illuminating the understudied targets in three main druggable protein families: GPCR, kinase and ion channels... and beyond. These e-IDG sessions will be hosted on Zoom Webinar platform and will feature two speakers giving 20 minute talks on a theme and allowing for some “mingling” and Live Q&A. Examples of themes are; Kinase, GPCR, Ion Channel, Informatic databases and tools, Machine Learning, Novel Technologies, Proteomics, Bio-Assays, Mouse resources, Compound screening. Advertisement and announcements of IDG e-Symposium Series will be made via IDG social media outlets, Newsletter, and website. The symposium sessions will be recorded and posted on IDG YouTube Channel and DruggableGenome.net.

Fall 2021 – September, October, November
Day: Odd-week Thursdays (September 16; October 7, 21; November 4, 18) - 5 total
Time: 9-10 AM PT /10-11 AM MT / 12-1 PM ET / 17-18 UK

Themes:
  • Sept. 16 – Kinase
  • Oct. 7 – GPCR
  • Oct. 21 – Informatics tools
  • Nov. 4 – Kinases
  • Nov. 18 – Ion Channels

Date: November 18, 2021
Theme: Ion Channel
Speaker: Dr. Henry Colecraft, Ph.D. ( Colombia) "Regulating Ion Channel Function and Expression With Engineered Nanobodies"
Speaker: Dr. Markus Delling, Ph.D. ( UCSF) "Illuminating the function of the dark matter polycystin channels"
Tags: #idg #drugdiscovery #ionchannels #nanobodies #polycstinchannels #proteinfunction #proteinexpression
Registration: click this link https://e-idg-symposium-series-nov182021.eventbrite.com

Date: November 4, 2021
Theme: Kinases
Speaker: Dr. Jian Jin, Ph.D. ( ISMMS) "Discovery of Kinase PROTACs as Potential Cancer Therapies"
Speaker: Dr. David Drewry ( UNC) "The Kinase Chemogenomic Set (KCGS): A resource for kinase vulnerability identification"
Tags: ##idg #drugdiscovery #Kinases #Protacs #SGC #KinaseInhibitorSet #cancer
Registration: click this link https://e-idg-symposium-series-nov042021.eventbrite.com

Date: October 21, 2021
Theme: Informatics Tools
Speaker: Anna Pamela Calinawan (Pei Wang Lab, ISMMS) "Pancancer Kinase Enrichment Analysis Provides Insights into Immunogenic Signaling Pathways"
Speaker: Dr. Alexander Lachmann (Avi Ma'ayan Lab, ISMMS) "PrismExp, blitzGSEA and bridgeGSEA: Incorporating Gene Function Predictions within GSEA"
Speaker: Eryk Kropiwnicki (Avi Ma'ayan Lab, ISMMS) "DrugShot: Querying Biomedical Search Terms to Retrieve Prioritized Lists of Small Molecules"
Tags: #idg #drugdiscovery #InformaticsTools #EnrichmentAnalysis #PrismExp #blitzGSEA #bridgeGSEA #DrugShot
Registration: click this link https://e-idg-symposium-series-oct212021.eventbrite.com/

Date: October 7, 2021
Theme: GPCR
Speaker: Dr. Jonathan Fay, PhD (UNC) "Active state ensemble of an itch receptor revealed by cryo-EM"
Speaker: Dr. Vsevolod "Seva" Katritch, PhD (USC) "Giga-Scale virtual screening for GPCR ligand discovery with V-SYNTHES technology"
Tags: #idg #drugdiscovery #GPCR #cryo-EM #V-SYNTHES #virtualscreening #structural_biology #ligand
Registration: click this link https://e-idg-symposium-series-oct072021.eventbrite.com/

Date: September 16, 2021
Theme: Kinases
Speaker: Dr. Susan Taylor, PhD (UCSD) "Introduction to PKA Cb"
Speaker: Dr. Jinae Roa, PhD (UCSD) "Retina: Window into PKA signaling in Neurons"
Speaker: Dr. Stephan Schürer, PhD (UofMiami) "The Dark Cancer Kinome: Untapped Opportunities to Target Understudied Kinases in Cancer"
Tags: #idg #drugdiscovery #drugrepurposing #rarediseases #druggability #AI #machinelearning
Registration: click this link https://e-idg-symposium-series-sept162021.eventbrite.com/